Glymphatics of the CNS, a Biodynamic Orientation

Advanced Primer

Glymphatics of the CNS, a Biodynamic Orientation


Recordings now available for access anytime.



FEE: $400.00

Recordings will be made available for participants for 12 months.


Seminar Summary

The body has an extracellular network, the interstitial system which interconnects with the vascular and lymphatic systems, all of which are contiguous with the Central Nervous System. Within the Central Nervous System this network has been coined the “Glymphatic System” originally “discovered” by Danish Neuroscientist Maiken Nedergaard in 2013. 

Since 2013 in the scientific and medical disciplines there has been further elucidation of some of the underlying mechanisms of this system including newer anatomic and physiologic features within the CNS not thought to exist. As well as a fourth meningeal layer which turns over the assumption of a three layer dura system.

This advanced primer for Biodynamic Craniosacral Therapists, explores the latest understandings of the Glymphatic System and mechanisms involved. From the role of microglia and the movement of interstitial fluid within perivascular (PVS) space, cerebrospinal fluid and blood; to the role of meningeal lymphatic vessels (MLV) – originally named by Italian physician Paulo Mascagni in 1787, yet finally seen by electron-microscopy and acknowledged in 2014. We will also discuss the role of the fourth meningeal layer – the subarachnoid lymphatic-like membrane (SLYM).

Having a working knowledge of this system, and how some post session processes may arise is important for supporting clients with a variety of challenges ranging from traumatic brain injuries, concussions, stroke, seizures, MS, parkinson’s, alzheimer’s, dementia, brain tumors, autism spectrum and post viral and microbial conditions including Covid-19, complex pain, and post surgeries to name a few. 

The primer will include experiential exercises using somatic based meditations, case studies and ways to approach being  with the Glymphatic System and CNS from a biodynamic approach.

Part One: Introduces the Glymphatic System and how bodily movements such as breath and circulation support this systems function. 

Part Two: Explores Glial Cells and brain waves states that occur in sleep, which the Glymphatic System functions through. The relationship with tidal phenomena, and how Biodynamics can support better sleep as a practice. 


Seminar Objective

On completion of the seminar, participants will summarize and relay the history, latest discoveries and theories related to the Glympthatic System. A capacity to demonstrate a working understanding of the anatomy and physiology of this system, integrated into overall knowledge of the central nervous system, including the movements of cerebrospinal fluid and interstitial fluid. Participants will be able to orient to this system, feel it within themselves though awareness practices, and also negotiate supporting this system when with clients. A working knowledge will be developed around various health conditions that are impacted by or impact the Glymphatic System and how to support them with Craniosacral Biodynamics.

Seminar Type

A  16-hour online in-person seminar. Synchronous and Asynchronous options. Complete recordings of the live seminar will be available for 12-months from seminar completion. 

Seminar Format

Body of Wonder Seminars are designed with layers of experience and learning opportunities in mind. The intention is to support people sensing, feeling and becoming deeply connected with the work. This seminar combines didactic with experiential practices.

Seminar Topics

The Glymphatics of the CNS, a Biodynamic Orientation consists of the following core topics that are built upon with further topics.  

  1. The History and feature of Glymphatic System
  2. Fluid Interconnection – Neuroscience & Medical History of Cerebrospinal Fluid Study
  3. Glial Cells, the Interstitial & Lymph System 
  4. Cerebrospinal Fluid incorporating new understandings of the Glymphatic System
  5. The 4 Meninges – Intro to SLYM and Meningeal Lymph System
  6. Para-& Perivascular Space and Brain Lymphatics
  7. Venus Sinus – Glymph, Brain, Cervical  Lymph 
  8. Glymphatics and Sleep

Seminar Outcome

Participants will start to develop a capacity for the following:


Describe the history and recent discoveries in neuroscience related to the Glymphatic System.

Discuss neuroscience and medicines history of Cerebrospinal Fluid discovery and study. 

  • Understand and orient to the anatomy and physiology of the Glymphatic System.
  • Describe and discuss the function of the Glymphatic System and it’s role in sleep, brainwave states, sustaining health and relationship with tidal phenomena. 
  • Describe and discuss the Cranial Sacral System that includes the fourth meningeal layer – SLYM and Meningeal Lymph system.
  • Describe and sense the fluctuation of cerebrospinal fluid within the CNS based on recent scientific discoveries of its movement patterns.
  • Negotiate and establish a spacious orientation to support Glymph, Lymph and Interstitial system functions in clients.
  • Develop practitioner listening, palpation, and perceptual skills that support working with the Glymph, Lymph and Interstitial systems as a whole.

About the educator

Prue Jeffries, CMT, RCST®, MSME/T is a Biodynamic Craniosacral Teacher and Continuum Teacher. In her personal practice Prue has worked extensively with Traumatic Brain Injuries and Neurological Diseases for over 15 years. Regularly seeing people in coma, with Chronic traumatic encephalopathy (CTE) (before it was acknowledged to exist), concussions, seizures, Parkinson’s, MS, dementia, post-viral and microbial conditions now including Covid-19, autism spectrum and brain tumors.  She brings her experiential working knowledge and experience with latest science to dive into this exciting topic that can support practitioners and their clients.


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